Nigeria Scales Up Mpox Prevention with Targeted Vaccination in High-Burden States
September 1, 2025
Nigeria’s targeted mpox vaccination campaign marks a vital step in protecting high-risk groups and reinforcing outbreak response across 12 states. Backed by WHO, UNICEF, and Gavi, the campaign is deploying 30,100 MVA-BN doses to frontline workers, immunocompromised individuals, and those exposed to confirmed cases. With mpox resurging after decades of absence and recent spikes in cases and deaths, the initiative is timely and strategic. Community voices reflect growing trust in vaccines, while officials emphasize cross-border health security. Early results show strong uptake, reinforcing the importance of collaboration, surveillance, and vaccination in curbing transmission and safeguarding vulnerable populations.
Nigeria’s newly launched mpox vaccination campaign represents a strategic milestone in outbreak prevention and response. Coordinated by the Federal Government through the National Primary Healthcare Development Agency, the ten-day campaign spans 12 high-burden states, including Plateau, Rivers, Delta, and Benue. Supported by WHO, UNICEF, and Gavi, the initiative deploys 30,100 MVA-BN vaccine doses, with priority given to frontline health workers, immunocompromised individuals, and those with confirmed exposure.
The stakes are high. Mpox re-emerged in Nigeria in 2017 after nearly 40 years of absence and has since caused significant morbidity and mortality. As of mid-August 2025, Nigeria had reported over 1,100 suspected cases, 283 laboratory-confirmed infections, and four deaths across 32 states. By focusing on at-risk populations and delivering two-dose regimens, Nigeria is aiming to reduce transmission chains while protecting those most vulnerable.
Community response has been encouraging. Residents in Benue and Cross River voiced relief at vaccine availability, while health workers in Plateau reported increased confidence in serving their communities. Local testimonies illustrate the role of trust and education in driving vaccine uptake, especially in rural and underserved areas.
Government and international partners have framed the campaign as a joint achievement in strengthening global health security. WHO has trained vaccination teams, coordinated logistics, and ensured cold-chain integrity, while also supporting risk communication and digital monitoring. Over 19,000 individuals have already been vaccinated, signaling strong early momentum.
Nigeria’s campaign is part of WHO’s broader global strategy to expand vaccine access, integrate immunization with surveillance, and reinforce outbreak preparedness. By combining vaccination, testing, and public awareness, Nigeria is positioning itself as a regional leader in mpox response. Sustained collaboration and timely vaccine supply will be critical to consolidating these gains and preventing further spread.