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New case of more spreadable mpox detected

January 20, 2025

The UK Health Security Agency (UKHSA) has confirmed a new case of Clade Ib mpox in East Sussex, bringing the total number of cases in England to six since October 2024. The individual, recently returned from Uganda where the virus is spreading, is receiving specialist care at Guy’s and St Thomas’ NHS Foundation Trust. Clade Ib mpox, first detected in Central Africa, spreads more easily through human contact and presents with symptoms such as fever, pus-filled lesions, and fatigue. While UKHSA Deputy Director Dr. Meera Chand assures the public that the risk remains low, contact tracing efforts are underway to contain potential spread.

A new case of Clade Ib mpox has been reported in East Sussex, the UK Health Security Agency (UKHSA) announced, marking the sixth confirmed case in England since October 2024. The infected individual recently traveled from Uganda, where community transmission of this more transmissible variant is ongoing. They are now receiving specialist care at Guy’s and St Thomas’ NHS Foundation Trust.

Clade Ib mpox, first identified in Central Africa, is notable for its enhanced human-to-human transmissibility. Symptoms include fever, headaches, pus-filled lesions, and extreme fatigue. Despite the concerning nature of this variant, UKHSA Deputy Director Dr. Meera Chand reassures the public that the overall risk to the UK population remains low. The agency is conducting robust contact tracing efforts to mitigate potential transmission and ensure rapid intervention where necessary.

The previous five cases in England included four connected through household contact, with the first identified in London in October and the others in Leeds and other areas. This most recent case is not linked to the earlier ones, suggesting isolated incidents tied to international travel.

The emergence of Clade Ib mpox highlights the continued need for global vigilance against infectious diseases. The UKHSA’s proactive approach, including specialist treatment and contact tracing, reflects a strong public health response to minimize risks. However, as global travel facilitates the spread of infectious diseases, maintaining robust surveillance systems and public awareness remains critical in controlling outbreaks. The situation underscores the importance of continued collaboration between nations to address the evolving challenges posed by mpox and similar threats.

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