Mpox warning issued in UK after cases spread in Europe
October 27, 2025
UK health authorities are calling on eligible individuals—particularly gay, bisexual, and other men who have sex with men—to get vaccinated against mpox as a new strain, clade Ib, spreads across Europe and the U.S. Although most UK cases remain linked to travel, community transmission abroad signals growing global circulation. The UK Health Security Agency stresses that vaccination remains the best protection, even as studies on this new strain continue. With Pride season approaching and memories of 2022’s outbreak still fresh, timely vaccination and awareness can prevent resurgence and protect vulnerable communities from another painful and disruptive wave of infection.
The UK Health Security Agency (UKHSA) has issued a renewed warning on mpox vaccination as a new strain, clade Ib, circulates in parts of Europe and the United States. Although only 16 cases have been reported in the UK so far, all within England, the pattern of transmission in other countries suggests emerging community spread. For now, most UK cases are linked to travel abroad—but public health officials caution that vigilance and vaccination are essential to prevent domestic outbreaks.
The mpox vaccine, already part of the UK’s immunization program for those at elevated risk, remains a cornerstone of prevention. While existing data show the vaccine is 75–80% effective against clade II mpox, protection is also expected against clade Ib. Health officials, including Dr. Katy Sinka of UKHSA, continue to emphasize the importance of vaccination for those with multiple sexual partners, who participate in group sex, or who visit sex-on-premises venues.
The Terrence Higgins Trust echoed this urgency, noting that although mpox is typically described as mild, its symptoms—painful lesions, fever, fatigue, and swollen lymph nodes—can cause severe discomfort and isolation. Chief Executive Richard Angell urged individuals to get vaccinated ahead of winter Pride events and to seek care immediately if symptoms appear.
The 2022 outbreak revealed the cost of delayed action and limited access to countermeasures. This time, the infrastructure exists—but its success depends on participation and awareness. Mpox’s continued spread reminds us that global mobility, sexual health, and community engagement are deeply interconnected. Vaccination is not just a personal choice but a collective act of protection, ensuring the hard-earned progress in containing mpox is not undone by complacency.