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Mpox Vaccination Rates Highest Among Cisgender Sexual Minority Men

December 10, 2024

A Rutgers Health survey of LGBTQ+ individuals in New York and New Jersey revealed high Mpox vaccination rates among cisgender men, gay-identified participants, and full-time employees during the 2022 outbreak. Despite targeted campaigns, many still struggled with appointment accessibility due to limited availability and inconvenient hours. The use of the smallpox vaccine Jynneos helped curb infections, though concerns about long-term immunity persist. Researchers stress the need for updated efficacy data as global Mpox cases rise. Addressing vaccination access and monitoring immunity levels are essential for strengthening public health responses and reducing future outbreak risks.

During the 2022 Mpox outbreak, a Rutgers Health survey highlighted significant vaccination uptake within the LGBTQ+ community in New York and New Jersey, particularly among cisgender men, gay-identified individuals, and full-time employees. The study, published in the Journal of Community Health, reported that 90.9% of cisgender men and 95.1% of gay-identified participants either received or intended to get vaccinated, reflecting the effectiveness of a targeted vaccination campaign focused on high-risk groups.

However, barriers to vaccine access persisted. More than half of survey respondents reported moderate to severe difficulty securing appointments due to limited availability, rapidly filled slots, and vaccinations offered primarily during working hours. This underscored the critical need for broader outreach and more flexible vaccination schedules.

Despite supply challenges, the U.S. adopted a dose-sparing strategy using the smallpox vaccine Jynneos, administering smaller doses intradermally to stretch limited supplies. While this approach raised concerns about efficacy, the Centers for Disease Control and Prevention reported that unvaccinated individuals were 14 times more likely to contract Mpox, suggesting the strategy was largely effective.

Looking forward, questions about long-term immunity remain. Rutgers researchers emphasized the importance of investigating how durable vaccine-induced immunity is, especially as Mpox cases rise globally. Understanding whether individuals vaccinated in 2022 still retain protection could guide booster shot recommendations and future vaccination strategies.

Addressing accessibility gaps, ensuring vaccine availability, and conducting further research are vital steps to containing future Mpox outbreaks while promoting equitable healthcare access for vulnerable communities.

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