Mpox still present in Virginia, as VDH tracks multiple cases in the commonwealth
September 3, 2025
Mpox, first detected in Virginia during the 2022 outbreak, continues to persist even as case numbers remain lower than in the initial surge. The Virginia Department of Health reports 23 cases so far in 2025, nearly matching the total for all of 2024. Transmission occurs primarily through close or sexual contact, with rashes serving as the most identifiable symptom. Men account for 95 percent of cases, and individuals with HIV or other immunocompromising conditions are most vulnerable to severe outcomes. Public health officials stress vaccination, especially for those with multiple partners, to reduce risk and protect communities across the commonwealth.
Mpox remains a public health concern in Virginia, even as the number of cases is far lower than during the 2022 outbreak. The Virginia Department of Health has already recorded 23 cases in 2025, compared with 27 in all of 2024, signaling that transmission continues at a steady pace. Dr. Brandy Darby, director of surveillance and investigation, emphasized that while cases are not at crisis levels, they should not be dismissed.
The virus spreads through close contact, including sexual contact, and presents most often with a painful, itchy rash that can appear in sensitive areas of the body. Vulnerable groups include individuals with weakened immune systems, infants under 1 year of age, pregnant or breastfeeding women, and those with a history of eczema. Severe illness is more likely when mpox occurs in individuals co-infected with HIV or other immunocompromising conditions. Since 2022, Virginia has recorded two deaths and multiple hospitalizations linked to mpox.
Men account for approximately 95 percent of reported cases, aligning with national trends that show the virus disproportionately affects sexual and social networks of men who have sex with men. Yet health officials stress that anyone in close contact with an infected person can contract the virus.
Vaccination remains one of the most effective tools for prevention. The Virginia Department of Health strongly encourages vaccination for sexually active individuals, particularly those with multiple partners. Vaccination not only reduces the risk of infection but also mitigates the severity of illness if exposure occurs.
The persistence of mpox in Virginia underscores the need for continued vigilance, public awareness, and expanded vaccination access. Health officials warn that complacency could allow outbreaks to grow. A proactive approach that emphasizes prevention, early detection, and community education remains essential to protect vulnerable populations.