First case of newer mpox variant detected in Ireland

February 6, 2025
Ireland has detected its first case of Clade 1 Mpox in a resident who recently returned from the Democratic Republic of Congo. The Health Service Executive (HSE) reassures the public that the risk remains low, with the patient receiving specialist care in Dublin. While Clade 1 is more transmissible and severe than Clade 2, those vaccinated or previously infected are considered protected. Ireland has recorded only eight Clade 2 cases in 2025. Global health officials remain concerned about the ongoing outbreaks in Africa, prompting mass vaccine shipments. Ireland continues to monitor the situation closely, ensuring rapid response capabilities.
Ireland has reported its first case of Clade 1 Mpox, the more severe and transmissible strain of the virus, in a resident returning from the Democratic Republic of Congo. The Health Service Executive (HSE) has assured the public that the risk remains low, with the patient receiving specialized care in Dublin. While Ireland has previously recorded Clade 2 Mpox cases, this is the first detection of Clade 1, which has been fueling outbreaks across Central and West Africa since 2023.
Mpox, caused by a virus in the same family as smallpox, spreads through close physical contact, including skin-to-skin interactions, shared personal items, and prolonged face-to-face exposure. Symptoms include flu-like illness, followed by painful, pus-filled skin lesions that can last up to a month. While many cases resolve within 14 to 21 days, severe infections can be fatal, particularly among vulnerable groups such as children.
Global health experts remain concerned about the escalating spread of Clade 1, leading the World Health Organization (WHO) to declare it a public health emergency in 2024. In response, millions of vaccine doses are being deployed to heavily affected regions in Africa. While imported cases have been reported in Sweden, Germany, India, Thailand, Canada, and the U.S., little onward transmission has occurred.
Ireland’s HSE continues to monitor the situation closely, maintaining a proactive approach. The recent opening of 12 new Mpox vaccination sites across England highlights the urgency of global preparedness. Irish health authorities urge vigilance, especially among individuals returning from high-risk areas, and recommend vaccination for at-risk populations to mitigate potential outbreaks.