Conjunctivitis, impaired vision top mpox complications of the eyes
February 7, 2025
A new meta-analysis published in the Journal of Infectious Diseases highlights conjunctivitis as the most common mpox-related eye complication, followed by impaired vision, keratitis, and eye lesions. Researchers stress the need for early recognition, routine eye exams, and timely treatment, particularly in endemic regions like Africa and among immunocompromised patients. The study underscores the risk of keratitis, which, if untreated, can lead to corneal ulceration and vision loss. Experts call for preventive strategies such as vaccination and antiviral treatments to mitigate disease severity and complications, emphasizing the necessity of further research to refine clinical guidelines and interventions.
A comprehensive meta-analysis published in the Journal of Infectious Diseases has identified conjunctivitis as the most frequent mpox-related eye complication, affecting nearly 9% of cases. Other significant complications include impaired vision (4.3%), keratitis (3.4%), and eye lesions (3.4%). The findings reinforce the importance of early detection and management, particularly in mpox-endemic regions such as Africa and among immunocompromised individuals.
Keratitis, though less common, presents a serious risk, as delays in diagnosis and treatment can lead to corneal ulceration and permanent vision loss. The study suggests that mpox-related ocular complications may stem from direct viral invasion of ocular tissues or immune-mediated damage, with severity influenced by infection progression, patient demographics, and access to healthcare.
Experts stress that routine eye examinations and early referrals to ophthalmologists should be standard practice in mpox care to improve patient outcomes. Preventive measures, including vaccination and timely antiviral interventions, are critical to reducing disease severity and mitigating complications such as keratitis and long-term vision impairment.
Despite the study’s significance, researchers acknowledge variability in the presentation and documentation of mpox-related eye conditions, indicating a need for standardized clinical guidelines. Future research should explore risk factors and targeted intervention strategies to refine public health responses.
Given the potential for severe ophthalmic complications, healthcare providers must integrate ocular screenings into mpox management protocols. The study’s findings underscore the urgency of strengthening preventive measures, enhancing clinical surveillance, and ensuring equitable access to timely medical interventions, particularly in high-risk populations.